Dimeric Cinchona alkaloids

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The Amorphous Cinchona Alkaloids

Quinoidine was greater than that of Quinine and this honour has often been awarded to it since, though very little of the drug appears to have been used except as a tonic for horses. Major Waters' recent paper in the IMG seems to be having a greater effect on its sale. In every Quinine factory Quinine alone has been the important product. The other alkaloids are listed and occasionally one or o...

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The Alkaloids of Cinchona

?n observations on the action o alkaloids in causing disappearance o parasites during an acute attack. Reports were received: , 7 (1) From Colonel Harvey who tinted 7 cases of benign tertian malaria with q bisulphate, 10 grains for 70 kilogrammes 'body weight. The drug was dissolved m dilute sul Phuric acid, one dose was given before break fast and one before the evening mea . Eleven patients w...

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Therapeutics of the Cinchona Alkaloids

Dear Sik,?We have read with great interest the admirable review of the recent work on Therapeutics of the Cinchona Alkaloids, which appeared in your issue of November 1922, Vol. LVIT, No. 11, by Major R. N Chopra. The subject is of such paramount importance that this article is sure to be read and quoted as a valuable review of the present position, and we, therefore, think that the earliest op...

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Bioactive cinchona alkaloids from Remijia peruviana.

Three known Cinchona alkaloids of the quinine type, quinine (1), cupreine (2), cinchonine (3), and the possible artifact cinchonine-HCl (3-HCl), along with two new ones, acetylcupreine (4) and N-ethylquinine (5), have been isolated from the bark of Remijia peruviana (Rubiaceae). Their stereochemical structures were established by high resolution NMR spectroscopy. Alkaloids 2-4 had antifeedant e...

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An Overview of Cinchona Alkaloids in Chemistry

Cinchona alkaloids (Figure 1.1), isolated from the bark of several species of cinchona trees, are the organic molecules with the most colorful biography [1]. Their history dates back to the early seventeenth century when they were first introduced into the European market after the discovery of the antimalarial property of cinchona bark and the subsequent isolation of its active compound, quini...

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ژورنال

عنوان ژورنال: Molecular Diversity

سال: 2015

ISSN: 1381-1991,1573-501X

DOI: 10.1007/s11030-014-9563-1